Substantial Body
Weight Reduction
Patients typically lose 10% to 15%+ of their starting body weight by reducing both overall body fat and harmful abdominal (visceral) fat.*

Available
Subcutaneous Injection
Semaglutide is a medication that mimics the action of GLP-1, a naturally occurring hormone involved in appetite regulation, blood sugar control, and digestion. It is a GLP-1 receptor agonist that can help reduce appetite and food intake when used as part of a medically supervised weight management plan.


Self-Injecting Guide
Step-by-step instructions for safe and easy injections.
Temperature Controlled Packaging
Insulated packaging protects your medication during shipping.
Compounded Semaglutide Vial
Multi-dose vial prepared by a licensed U.S. compounding pharmacy.
Sterile Syringes
Individually wrapped syringes for your prescribed doses.
Alcohol Swabs
Clean the vial top and injection site before each dose.
Gauze Pads
Apply gentle pressure to the injection site afterward.
Cold Pack
Keeps your vial cool until you can refrigerate it.
Self-Injecting Guide
Step-by-step instructions for safe and easy injections.
Temperature Controlled Packaging
Insulated packaging protects your medication during shipping.
Compounded Semaglutide Vial
Multi-dose vial prepared by a licensed U.S. compounding pharmacy.
Sterile Syringes
Individually wrapped syringes for your prescribed doses.
Alcohol Swabs
Clean the vial top and injection site before each dose.
Gauze Pads
Apply gentle pressure to the injection site afterward.
Cold Pack
Keeps your vial cool until you can refrigerate it.
Your compounded semaglutide comes in a multi-dose vial and is administered as a subcutaneous injection. Your care team will provide clear instructions on your prescribed dose, syringe use, injection technique, and storage.

Step 1
Confirm the medication name and prescribed dose.
Step 2
Check the vial concentration against your prescription.
Step 3
Use a new sterile syringe and needle for every injection.
Step 4
Follow the storage instructions provided by your pharmacy.
Step 5
Follow your care team's instructions for injection sites and technique.

Semaglutide has been extensively studied for weight management, blood sugar control, and related metabolic health outcomes. Clinical trials have evaluated its effectiveness, safety, dosing, and long-term use across diverse patient populations.
Research has reported meaningful reductions in body weight and improvements in several cardiometabolic measures when semaglutide is used alongside lifestyle changes. Explore the evidence behind semaglutide through peer-reviewed clinical studies, systematic reviews, and scientific whitepapers.

Patients typically lose 10% to 15%+ of their starting body weight by reducing both overall body fat and harmful abdominal (visceral) fat.*
It acts directly on brain receptors to signal fullness, curbing hunger and reducing cravings for high-calorie foods.
By slowing down stomach emptying, it keeps you feeling fuller for much longer after eating smaller meal portions.
Increases natural insulin production in response to meals and improves insulin sensitivity, lowering HbA1c levels and helping prevent or manage Type 2 diabetes.
Clinical trials show reduced risk of major adverse cardiovascular events (such as stroke or heart attack) by lowering blood pressure and systemic inflammation.
Emerging research indicates benefits in slowing chronic kidney disease progression and reducing liver fat (steatotic liver disease).
*Weight-loss results vary by individual. Clinical trial results are based on specific populations, doses, treatment durations, and lifestyle interventions and may not reflect results with compounded semaglutide.
Starting a GLP-1 medication can come with side effects, especially as your body adjusts to treatment. Most gastrointestinal side effects are more common when starting treatment or increasing the dose. Our care team is here to help you manage common symptoms and answer questions throughout your weight loss journey.
3 simple steps
Getting started should feel simple.
Answer a few questions about your health history, goals, medications, and overall health. It takes about 5 to 15 minutes.

Meet with a licensed provider by video or phone. They’ll review your health information and lab results to determine whether treatment is medically appropriate. If prescribed, fill your prescription at a pharmacy or choose Ongo Weight Loss for medication delivery and ongoing care.

Choose the treatment plan that works for you. If prescribed through Ongo, your medication is shipped in discreet packaging from a licensed U.S. pharmacy with tracking. Your care team provides regular check-ins, answers your questions, and makes treatment adjustments when medically appropriate.

Semaglutide is administered as a subcutaneous injection, typically once weekly. Your healthcare provider will provide your specific dose, injection volume, and instructions.